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Study: Exposure to certain chemicals in womb may lead to childhood weight gain

A recent study suggests that babies exposed to certain chemicals while in the womb may have a higher likelihood of experiencing rapid weight gain during early childhood. The research was published in the Environmental Health Perspectives journal.

This study has established a connection between exposure to endocrine-disrupting chemicals in utero and a substantial increase in a child’s body mass index (BMI) from birth to 9 years of age.

The research points to polyfluoroalkyl substances (PFAS), often referred to as “forever chemicals,” as being responsible for the excessive weight gain in unborn children. These chemicals are derived from fungicides and pesticides and break down slowly within the body. They are commonly found in everyday items, including non-stick cookware, cosmetic products, plastic food containers, and can even be present in some meat and fish if the animals have been exposed to contaminated environments. These substances interact with the human endocrine system by mimicking natural hormones.

The research methodology involved analyzing data from over 1,900 pairs of mothers and children in Spain, collected between 2003 and 2008. The women, whose racial background was not specified, provided blood and urine samples during pregnancy, from which the researchers measured the concentration of endocrine-disrupting chemicals in their bodies. Subsequently, the scientists monitored their children’s BMI at various points up to the age of 9.

The analysis revealed that babies with higher exposure to endocrine-disrupting chemicals before birth were more likely to be born smaller than the study’s average but then experience rapid growth in their early years.

Furthermore, exposure to two specific chemicals was linked to a greater risk of accelerated BMI gain in babies who were born larger than the study’s average.

The study’s lead author, Parisa Montazeri, suggests that one possible reason for this association is that endocrine-disrupting chemicals can mimic or interfere with hormones involved in the breakdown of food for energy. This disruption can alter the body’s hunger signals or its sensitivity to sugar and fats, potentially contributing to weight-related issues.

Montazeri, who serves as a scientific coordinator at the Barcelona Institute for Global Health, points out that a rapid increase in BMI during childhood is linked to health problems in adulthood, including obesity, fatty liver disease, cardiovascular disease, and diabetes. By identifying early factors that contribute to these health issues, healthcare professionals may be better equipped to intervene and reduce the risk of disease later in life.

She also noted that while endocrine-disrupting chemicals are one factor that helps explain the increasing obesity rates, they should be considered alongside other lifestyle factors such as sedentary habits and dietary choices.

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